Sex Hormone Binding Globulin (SHBG) is a carrier protein produced mostly in the liver. SHBG binds to testosterone, DHT and estradiol and circulates the hormones throughout the body.

SHBG levels can be both unduly low (meaning there are more unbound sex hormones available for use) and unduly high (meaning fewer unbound sex hormones are available). Elevated SHBG levels can result from diets low in protein, leading to decreased testosterone bioactivity and deleterious effects on sexual function, fertility and bone density, as well as a higher incidence of certain cancers.

Low SHBG, meanwhile, tends to correlate with obesity, type 2 diabetes, high blood pressure and hypothyroidism.

Because SHBG regulates how much hormones are delivered to the body’s tissues, it is vital to ensure that your levels are in the normal range. For a man, that’s 10-57 nmol/L, and for a woman, it’s 18-144 nmol/L.

In this article, we’ll discuss ways to optimise your hormonal lower profile by lowering elevated SHBG levels and thereby increasing your amount of free testosterone. We’ll also suggest a few methods for increasing low SHBG levels.